Manchester United will look to extend their lead at the top to 15 points when they host Norwich City in their English Premier League game.
Norwich were the last team to beat United in the league, and the Canaries will be hoping lightning strikes twice.
United will also have an eye on the mega Champions League clash against Real Tuesday, so Ferguson might rest some of his big stars and veterans.
"Tomorrow (Saturday) is the important one for us," Ferguson told reporters. "Tuesday will look after itself. That is an occasion whereas tomorrow is the mundane, practical situation in that we need to win.
"That is what the concentration is on. I can assure you the players will not be thinking about Tuesday at this moment in time. All week we've been talking about how important Norwich is."
United defender Patrice Evra has also stressed on the importance of keeping their control in the Premier League. "Every game is important now," he told the club's official website. "I hear a lot of people talking about the Treble and this is the wrong way (to do it) -- you have to think game-after-game.
"If we start to think about Madrid before Norwich, then you lose to Norwich. It's a big game and we have to win -- if we go into Tuesday after losing against Norwich, it's going to be a nightmare.
"The Premier League is the priority. We won't think about Madrid until Saturday, just after the game, and then we will have our recovery on Sunday. Every game is important. I even say friendly games with United are important."
United will have Robin Van Persie available after the injury scared suffered in the match against QPR last weekend, but Phil Jones is ruled out.
"Phil Jones starts running today," Ferguson added. "He's got a fight on his hands to be ready for Tuesday [Real Madrid] but we'll give him every chance. He won't be available for tomorrow (Norwich).
"We have no injury issues. Robin van Persie has trained this week -- he's available for tomorrow. His hip was very tender but he's okay now."
Expected lineups: Manchester United: De Gea; Rafael, Smalling, Evans, Evra; Nani, Anderson, Cleverley, Young; Rooney, Hernandez.
Norwich: Bunn; Martin, Bassong, Turner, Garrido; Howson, Johnson; Snodgrass, Hoolahan, Pilkington; Holt.
Prediction: 2-0 to United